Anti-IL1ß-monoclonal antibody in two adult patients with PFAPA Syndrome - a single centre experience
نویسندگان
چکیده
Background The periodic fever, aphthous stomatitis, pharyngitis and cervical adenitis (PFAPA) syndrome belongs to the rare nonhereditary autoinflammatory diseases and normally onsetting in childhood, but despite of tonsillectomy persisting or newly occurring in adulthood. The exact pathogenesis is not clear, but to our understanding it is an acquired autoinflammatory disease due to an unregulated production of cytokines. The common treatment varies from NSAIDS, colchicine, corticosteroids up to blocking IL1receptor.
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